TYPE | Statistical & Bio Seminar |
Speaker: | Dr. Rami Pugatch |
Affiliation: | Trieste |
Organizer: | Yariv Kafri |
Date: | 22.01.2017 |
Time: | 14:30 - 15:30 |
Location: | Lewiner Seminar Room (412) |
Abstract: | What determines the growth rate of a cell? why certain bacteria increase their dry mass exponentially in the right conditions? Is the distribution of doubling times universal? In this talk I will offer a novel universal model for cellular self-replication based on a network of self-replicating queues arranged in the von-Neumann architecture. I will explain how pipelining of self-replication allow cells to linearly increase the doubling rate by exponentially increasing the level of WIP (Work-In-Process), whenever decreasing the cycle time is impossible. I will explain how a simple generalization of Little's law applicable to self-replicating factories or queues that relates the doubling rate with the number of progenies concurrently under production, and the critical path duration, can be employed to predict a universal distribution of doubling times with excellent agreement with experimental measurements. |